Tag Archives: DNA origami

Nanoscale emoticons made with DNA — origami vs. tiles

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Hi :-). The smiley face you see here is about 4 mm (or 0.17 of an inch) in length, depending on the font size you are using. Imagine shrinking it by 40,000 times! That is about the size of the smiley face made with synthetic DNA using nanotechnology.

DNA nanotechnology has been around for over 30 years, but the major breakthrough in the field was the development of the DNA origami in 2006. The DNA origami enabled the construction of more complex structures in about a week. The basic principle of the method is that one long, single-stranded DNA gets folded into a certain shape by about 200 short, single strands of DNA segments, or “staples.” This is possible because a single strand of DNA always pairs up with a complementary strand to form a double strand. This approach can be used to create both 2- or 3-dimensional structures. (Read more on DNA origami here.) Continue reading –>

Adapted from Rothemund and Andersen (2012) Nature.

 

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Nanorobot to cure cancer? — the art of DNA origami

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The big question in developing a drug is how to deliver the drug to the target without affecting other healthy parts of the body. This question might be answered by the recently developed nanorobot.

Animation of the structure of a section of DNA...

Nanorobot was developed by the research team at the Harvard University, whose article was published in Sicence last month. The device utilizes DNA nanotechnology and has two key features: targeted delivery and conditional release of payload. Continue reading –>

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